Daryanti Saragih (2024) Beneficial effects of non-pharmacological interventions for post-stroke pain A meta-analysis

This meta-analysis evaluated the effectiveness of non-pharmacological interventions for managing post-stroke pain. Fourteen studies with 599 post-stroke patients were included, analyzing diverse interventions such as acupuncture, aquatic therapy, mirror therapy, and laser therapy. Pain reduction was significant immediately after intervention (SMD −0.79; 95% CI −1.06 to −0.53).

Subgroup analyses revealed that interventions like acupuncture and aquatic therapy were particularly effective for hemiplegic shoulder pain and complex regional pain syndrome, though less impactful for central post-stroke pain. Interventions lasting less than four weeks showed positive outcomes comparable to longer durations. Aquatic therapy was noted for its ability to enhance mobility and reduce pain with minimal strain.

Despite these benefits, the study highlighted the need for high-quality trials addressing central post-stroke pain and severe pain, as well as exploring combinations of pharmacological and non-pharmacological strategies for optimal pain management.